Loss of mortgage interest deduction — If you itemize, you can deduct home mortgage interest on the first $750,000 ($375,000 if married filing separately). The limit is $1 million ($500,000 if married filing separately) if you are deducting mortgage interest for a home purchased before Dec. 16, 2017.
Source: https://www.washingtonpost.com/business/2021/10/26/great-resignation-early-mortgage-payoff/